Citicoline(CDP Choline) is a precursor of phosphatidylcholine. As a type of phospholipid, phosphatidylcholine is an important component of cell membranes. When taken orally, Citicoline(CDP Choline) is metabolized to yield the free nucleotide，uridine and choline. Uridine and choline cross the blood-brain barrier，become incorporated into brain membrane phospholipids and increase the production of neurotransmitters in the central nervous system, including the synthesis of acetylcholine, noradrenaline and dopamine. In the brain, Citicoline(CDP Choline) stabilizes the cell membranes and inhibits the formation of cytotoxic free fatty acids. Numerous scientific studies have shown that Citicoline may be an effective alternative to phosphatidylcholine and has a measurable effect on memory for healthy individuals as well improving mild memory problems associated with aging. Citicoline, also known as Cytidine 5'-diphosphocholine and CDPcholine, has a widespread, but not exclusive use in brain health. The many years of use have caused an evolution in dosage, method of administration and selection of patients to which citicoline was given.
Citicoline seems to increase a brain chemical called phosphatidylcholine. This brain chemical is important for brain function. Citicoline might also decrease brain tissue damage when the brain is injured. Citicoline seems to be safe when taken short-term. The safety of long-term use is not known. Most people who take citicoline don't experience problematic side effects. But some people can have side effects such as insomnia, headache, diarrhea, low or high blood pressure, nausea, blurred vision, chest pains, and others.
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