2012年10月11日星期四

Galanthamine Hydrobromide

Galanthamine Hydrobromide is a kind of reversible cholinesterase inhibitor, have effect against anticholinesterase. It is a strong (reversible) cholinesterase inhibitor that increases the susceptibility of an organism to acetylcholine, and is an effective treatment for mild to moderate dementia of the Alzheimer's type. It is also an allosteric modulator at nicotinic cholinergic receptor sites potentiating cholinergic nicotinic neurotransmission. Both the acetylcholine and nicotine receptors have been suggested as areas related to cognitive impairment. Initially, Galanthamine extract was used in anesthesiology to antagonize the effects of non-depolarizing muscle relaxants, and since then it was rapidly introduced in other areas of medicine, i.e. neurology, ophthalmology, gastroenterology, intensive care and resuscitation, cardiology, physiotherapy.

Galanthamine Hydrobromide is widely applied to asthma, chronic obstructive pulmonary disease, GI bleeding, moderate hepatic or renal impairment, Parkinson's disease, seizures. When galanthamine is used to treat the symptoms of Alzheimer's disease, it works by increasing the amount of a certain natural substance in the brain that is needed for memory and thought. Galantamine may improve the ability to think and remember or slow the loss of these abilities in people who have Alzheimer's disease. Please consult the healthcare provider when you need this product.

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